Opposite monosynaptic scaling of BLP–vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory

Different emotional states lead to distinct behavioural consequences even when faced with the same challenging events. Emotions affect learning and memory capacities, but the underlying neurobiological mechanisms remain elusive. Here we establish models of learned helplessness (LHL) and learned hope...

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Bibliographic Details
Main Authors: Yang, Ying, Wang, Zhi-Hao, Jin, Sen, Gao, Di, Liu, Nan, Chen, Shan-Ping, Zhang, Sinan, Liu, Qing, Liu, Enjie, Wang, Xin, Liang, Xiao, Wei, Pengfei, Li, Xiaoguang, Li, Yin, Yue, Chenyu, Li, Hong-lian, Wang, Ya-Li, Wang, Qun, Ke, Dan, Xie, Qingguo, Xu, Fuqiang, Wang, Liping, Wang, Jian-Zhi
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947155/