Identification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapy
There is an increasing interest in development of novel anticancer agents that target oncogenes. We have recently discovered that nuclear factor of activated T cells 1 (NFAT1) is a novel regulator of the Mouse Double Minute 2 (MDM2) oncogene and the NFAT1-MDM2 pathway has been implicated in human ca...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Editorial Department of Journal of Biomedical Research
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946323/ |