Growth of Streptococcus mutans in Biofilms Alters Peptide Signaling at the Sub-population Level

Streptococcus mutans activates multiple cellular processes in response to the formation of a complex between comX-inducing peptide (XIP) and the ComR transcriptional regulator. Bulk phase and microfluidic experiments previously revealed that ComR-dependent activation of comX is altered by pH and by...

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Bibliographic Details
Main Authors: Shields, Robert C., Burne, Robert A.
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946182/