Preparation and clinical evaluation of a novel lozenge containing polaprezinc, a zinc-L-carnosine, for prevention of oral mucositis in patients with hematological cancer who received high-dose chemotherapy
We previously reported that oral ingestion of polaprezinc, a zinc-L-carnosine, suspended in sodium alginate solution prevents oral mucositis in patients receiving radiotherapy or high-dose chemotherapy. In the present study, we developed a novel preparation of polaprezinc and evaluated clinical effe...
Main Authors: | Hayashi, Hiroko, Kobayashi, Ryo, Suzuki, Akio, Yamada, Yuto, Ishida, Masayuki, Shakui, Toshinobu, Kitagawa, Junichi, Hayashi, Hideki, Sugiyama, Tadashi, Takeuchi, Hirofumi, Tsurumi, Hisashi, Itoh, Yoshinori |
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Format: | Online |
Language: | English |
Published: |
Springer US
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945687/ |
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