Platelet lysate as a substitute for animal serum for the ex-vivo expansion of mesenchymal stem/stromal cells: present and future

The use of fetal bovine serum (FBS) as a cell culture supplement is discouraged by regulatory authorities to limit the risk of zoonoses and xenogeneic immune reactions in the transplanted host. Additionally, FBS production came under scrutiny due to animal welfare concerns. Platelet derivatives have...

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Bibliographic Details
Main Authors: Astori, Giuseppe, Amati, Eliana, Bambi, Franco, Bernardi, Martina, Chieregato, Katia, Schäfer, Richard, Sella, Sabrina, Rodeghiero, Francesco
Format: Online
Language:English
Published: BioMed Central 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944312/