Platelet lysate as a substitute for animal serum for the ex-vivo expansion of mesenchymal stem/stromal cells: present and future
The use of fetal bovine serum (FBS) as a cell culture supplement is discouraged by regulatory authorities to limit the risk of zoonoses and xenogeneic immune reactions in the transplanted host. Additionally, FBS production came under scrutiny due to animal welfare concerns. Platelet derivatives have...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944312/ |