Soluble Tie2 overrides the heightened invasion induced by anti-angiogenesis therapies in gliomas

Glioblastoma recurrence after treatment with the anti–vascular endothelial growth factor (VEGF) agent bevacizumab is characterized by a highly infiltrative and malignant behavior that renders surgical excision and chemotherapy ineffective. Our group has previously reported that Tie2-expressing monoc...

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Bibliographic Details
Main Authors: Cortes-Santiago, Nahir, Hossain, Mohammad B., Gabrusiewicz, Konrad, Fan, Xuejun, Gumin, Joy, Marini, Frank C., Alonso, Marta M., Lang, Frederick, Yung, W.K., Fueyo, Juan, Gomez-Manzano, Candelaria
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941303/