Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas

Neuroblastoma (NB), a tumor of the sympathetic nervous system, is the most common extracranial solid tumor of childhood. We and others have identified distinct patterns of genomic change that underlie diverse clinical behaviors, from spontaneous regression to relentless progression. We first identif...

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Bibliographic Details
Main Authors: Naraparaju, Koumudi, Kolla, Venkatadri, Zhuang, Tiangang, Higashi, Mayumi, Iyer, Radhika, Kolla, Sriharsha, Okawa, Erin R., Blobel, Gerd A., Brodeur, Garrett M.
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941291/