Induced pluripotent stem cells in Parkinson's disease: scientific and clinical challenges

Induced pluripotent stem cells (iPSCs), which greatly circumvent the ethical issue of human embryonic stem cells (ESCs), can be induced to differentiate to dopaminergic (DA) neurons, and hence be used as a human disease model for Parkinson's disease (PD). iPSCs can be also utilised to probe the...

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Bibliographic Details
Main Authors: Xiao, Bin, Ng, Huck Hui, Takahashi, Ryosuke, Tan, Eng-King
Format: Online
Language:English
Published: BMJ Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941130/