Ag85A/ESAT-6 chimeric DNA vaccine induces an adverse response in tuberculosis-infected mice

The Mycobacterium tuberculosis (M. tb) antigens encoded by the 6 kDa early secretory antigenic target (esat-6) and antigen 85A (ag85a) genes are known to exert protective effects against tuberculosis in animal models. In addition, these antigens represent vaccine components that were tested in early...

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Bibliographic Details
Main Authors: Liang, Yan, Bai, Xuejuang, Zhang, Junxian, Song, Jingying, Yang, Yourong, Yu, Qi, Li, Ning, Wu, Xueqiong
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940052/