The dynamic interactome and genomic targets of Polycomb complexes during stem cell differentiation

While the core subunits of Polycomb group (PcG) complexes are well characterized, little is known about the dynamics of these protein complexes during cellular differentiation. We used quantitative interaction proteomics and genome-wide profiling to study PcG proteins in mouse embryonic stem cells (...

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Bibliographic Details
Main Authors: Kloet, Susan L., Makowski, Matthew M., Baymaz, H. Irem, van Voorthuijsen, Lisa, Karemaker, Ino D., Santanach, Alexandra, Jansen, Pascal W.T.C., Di Croce, Luciano, Vermeulen, Michiel
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939079/