Dcsbis (PA2771) from Pseudomonas aeruginosa is a highly active diguanylate cyclase with unique activity regulation

C-di-GMP (3’,5’ -Cyclic diguanylic acid) is an important second messenger in bacteria that influences virulence, motility, biofilm formation, and cell division. The level of c-di-GMP in cells is controlled by diguanyl cyclases (DGCs) and phosphodiesterases (PDEs). Here, we report the biochemical fun...

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Bibliographic Details
Main Authors: Chen, Ying, Liu, Shiheng, Liu, Cuilan, Huang, Yan, Chi, Kaikai, Su, Tiantian, Zhu, Deyu, Peng, Jin, Xia, Zhijie, He, Jing, Xu, Sujuan, Hu, Wei, Gu, Lichuan
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937426/