Overexpression of Plasmodium berghei ATG8 by Liver Forms Leads to Cumulative Defects in Organelle Dynamics and to Generation of Noninfectious Merozoites

Plasmodium parasites undergo continuous cellular renovation to adapt to various environments in the vertebrate host and insect vector. In hepatocytes, Plasmodium berghei discards unneeded organelles for replication, such as micronemes involved in invasion. Concomitantly, intrahepatic parasites expan...

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Bibliographic Details
Main Authors: Voss, Christiane, Ehrenman, Karen, Mlambo, Godfree, Mishra, Satish, Kumar, Kota Arun, Sacci, John B., Sinnis, Photini, Coppens, Isabelle
Format: Online
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937212/