Controlled bile acid exposure to oesophageal mucosa causes up-regulation of nuclear γ-H2AX possibly via iNOS induction
The results of the present study provide suggestion that not only acid reflux, but also non-acid reflux of bile may cause genotoxic stress. These aspects merit to be tested in wide spectrum of Barrett epithelial tissues.
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937172/ |