The Maternal Effect Genes UTX and JMJD3 Play Contrasting Roles in Mus musculus Preimplantation Embryo Development

During the process of embryonic development in mammals, epigenetic modifications must be erased and reconstructed. In particular, the trimethylation of histone 3 lysine 27 (H3K27me3) is associated with gene-specific transcriptional repression and contributes to the maintenance of the pluripotent emb...

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Bibliographic Details
Main Authors: Yang, Lei, Song, Li-Shuang, Liu, Xue-Fei, Xia, Qing, Bai, Li-Ge, Gao, Li, Gao, Guang-Qi, Wang, Yu, Wei, Zhu-Ying, Bai, Chun-Ling, Li, Guang-Peng
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935995/