NEDDylation promotes stress granule assembly

Stress granules (SGs) harbour translationally stalled messenger ribonucleoproteins and play important roles in regulating gene expression and cell fate. Here we show that neddylation promotes SG assembly in response to arsenite-induced oxidative stress. Inhibition or depletion of key components of t...

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Bibliographic Details
Main Authors: Jayabalan, Aravinth Kumar, Sanchez, Anthony, Park, Ra Young, Yoon, Sang Pil, Kang, Gum-Yong, Baek, Je-Hyun, Anderson, Paul, Kee, Younghoon, Ohn, Takbum
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935812/