Neutrophil Interactions with Epithelial Expressed ICAM-1 Enhances Intestinal Mucosal Wound Healing

A characteristic feature of gastrointestinal tract inflammatory disorders, such as inflammatory bowel disease, is polymorphonuclear neutrophil (PMN) transepithelial migration (TEM) and accumulation in the gut lumen. PMN accumulation within the intestinal mucosa contributes to tissue injury. While ep...

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Bibliographic Details
Main Authors: Sumagin, R, Brazil, JC, Nava, P, Nishio, H, Alam, A, Luissint, AC, Weber, DA, Neish, AS, Nusrat, A, Parkos, CA
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935657/