Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma

While primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide, it still does not have a clear mechanism that can explain all clinical cases of the disease. Elevated IOP is associated with increased accumulation of extracellular matrix (ECM) proteins in the trabecular meshwork (T...

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Bibliographic Details
Main Authors: Zhavoronkov, Alex, Izumchenko, Evgeny, Kanherkar, Riya R., Teka, Mahder, Cantor, Charles, Manaye, Kebreten, Sidransky, David, West, Michael D., Makarev, Eugene, Csoka, Antonei Benjamin
Format: Online
Language:English
Published: Taylor & Francis 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934076/