Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma
While primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide, it still does not have a clear mechanism that can explain all clinical cases of the disease. Elevated IOP is associated with increased accumulation of extracellular matrix (ECM) proteins in the trabecular meshwork (T...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Taylor & Francis
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934076/ |