Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation*

We previously established a mechanism of negative regulation of transforming growth factor β signaling mediated by the nuclear ADP-ribosylating enzyme poly-(ADP-ribose) polymerase 1 (PARP1) and the deribosylating enzyme poly-(ADP-ribose) glycohydrolase (PARG), which dynamically regulate ADP-ribosyla...

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Bibliographic Details
Main Authors: Watanabe, Yukihide, Papoutsoglou, Panagiotis, Maturi, Varun, Tsubakihara, Yutaro, Hottiger, Michael O., Heldin, Carl-Henrik, Moustakas, Aristidis
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933475/