Persister formation in Staphylococcus aureus is associated with ATP depletion

Persisters are dormant phenotypic variants of bacterial cells that are tolerant to killing by antibiotics1. Persisters are associated with chronic infections and antibiotic treatment failure1–3. In Escherichia coli, toxin/antitoxin (TA) modules have been linked to persister formation4–6. The mechani...

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Bibliographic Details
Main Authors: Conlon, Brian P., Rowe, Sarah E., Gandt, Autumn Brown, Nuxoll, Austin S., Donegan, Niles P., Zalis, Eliza A., Clair, Geremy, Adkins, Joshua N., Cheung, Ambrose L., Lewis, Kim
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932909/