Phenotypic research on senile osteoporosis caused by SIRT6 deficiency

Osteoporosis is a serious public bone metabolic disease. However, the mechanisms underlying bone loss combined with ageing, which is known as senile osteoporosis, remains unknown. Here we show the detailed phenotype of this disease caused by SIRT6 knock out (KO) in mice. To the best of our knowledge...

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Bibliographic Details
Main Authors: Zhang, De-Mao, Cui, Di-Xin, Xu, Ruo-Shi, Zhou, Ya-Chuan, Zheng, Li-Wei, Liu, Peng, Zhou, Xue-Dong
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932771/