Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

Obesity is the result of a long-term positive energy balance in which caloric intake overrides energy expenditure. This anabolic state results from the defective activity of hypothalamic neurons involved in the sensing and response to adiposity. However, it is currently unknown what the earliest obe...

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Bibliographic Details
Main Authors: Souza, Gabriela F. P., Solon, Carina, Nascimento, Lucas F., De-Lima-Junior, Jose C., Nogueira, Guilherme, Moura, Rodrigo, Rocha, Guilherme Z., Fioravante, Milena, Bobbo, Vanessa, Morari, Joseane, Razolli, Daniela, Araujo, Eliana P., Velloso, Licio A.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931679/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931679/

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