Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert−/− mice

Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert−/− mice

The role of telomerase reverse transcriptase (TERT) has been extensively investigated in the contexts of aging and cancer. Interestingly, Tert−/− mice exhibit additional but unexpected aggressive and depressive behaviors, implying the potential involvement of TERT function in mood control. Our condi...

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Bibliographic Details
Main Authors: Zhou, Q-G, Wu, H-Y, Zhou, H, Liu, M-Y, Lee, H-W, Liu, X, Devkota, S, Ro, E J, Zhu, D-Y, Suh, H
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931604/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931604/

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