Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment

To investigate whether overexpression of Bmi1 in lymphocytes can stimulate skeletogenesis by improving the osteogenic microenvironment, we examined the skeletal phenotype of EμBmi1 transgenic mice with overexpression of Bmi1 in lymphocytes. The size of the skeleton, trabecular bone volume and osteob...

Full description

Bibliographic Details
Main Authors: Zhou, Xichao, Dai, Xiuliang, Wu, Xuan, Ji, Ji, Karaplis, Andrew, Goltzman, David, Yang, Xiangjiao, Miao, Dengshun
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931581/