UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly

Early eukaryotic ribosome biogenesis involves large multi-protein complexes, which co-transcriptionally associate with pre-ribosomal RNA to form the small subunit processome. The precise mechanisms by which two of the largest multi-protein complexes—UtpA and UtpB—interact with nascent pre-ribosomal...

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Bibliographic Details
Main Authors: Hunziker, Mirjam, Barandun, Jonas, Petfalski, Elisabeth, Tan, Dongyan, Delan-Forino, Clémentine, Molloy, Kelly R., Kim, Kelly H., Dunn-Davies, Hywel, Shi, Yi, Chaker-Margot, Malik, Chait, Brian T., Walz, Thomas, Tollervey, David, Klinge, Sebastian
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931317/