Programming a topologically constrained DNA nanostructure into a sensor

Many rationally engineered DNA nanostructures use mechanically interlocked topologies to connect individual DNA components, and their physical connectivity is achieved through the formation of a strong linking duplex. The existence of such a structural element also poses a significant topological co...

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Bibliographic Details
Main Authors: Liu, Meng, Zhang, Qiang, Li, Zhongping, Gu, Jimmy, Brennan, John D., Li, Yingfu
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931013/