Trichostatin A Protects Liver against Septic Injury through Inhibiting Toll-Like Receptor Signaling

Sepsis, a serious clinical problem, is characterized by a systemic inflammatory response to infection and leads to organ failure. Toll-like receptor (TLR) signaling is intimately implicated in hyper-inflammatory responses and tissue injury during sepsis. Histone deacetylase (HDAC) inhibitors have be...

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Bibliographic Details
Main Authors: Kim, So-Jin, Park, Jin-Sook, Lee, Do-Won, Lee, Sun-Mee
Format: Online
Language:English
Published: The Korean Society of Applied Pharmacology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930282/