Reduced protein synthesis in schizophrenia patient-derived olfactory cells
Human olfactory neurosphere-derived (ONS) cells have the potential to provide novel insights into the cellular pathology of schizophrenia. We used discovery-based proteomics and targeted functional analyses to reveal reductions in 17 ribosomal proteins, with an 18% decrease in the total ribosomal si...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930119/ |