Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE

Prior to 2001 there was no standard for early management of severe sepsis and septic shock in the emergency department. In the presence of standard or usual care, the prevailing mortality was over 40-50 %. In response, a systems-based approach, similar to that in acute myocardial infarction, stroke...

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Bibliographic Details
Main Authors: Nguyen, H. Bryant, Jaehne, Anja Kathrin, Jayaprakash, Namita, Semler, Matthew W., Hegab, Sara, Yataco, Angel Coz, Tatem, Geneva, Salem, Dhafer, Moore, Steven, Boka, Kamran, Gill, Jasreen Kaur, Gardner-Gray, Jayna, Pflaum, Jacqueline, Domecq, Juan Pablo, Hurst, Gina, Belsky, Justin B., Fowkes, Raymond, Elkin, Ronald B., Simpson, Steven Q., Falk, Jay L., Singer, Daniel J., Rivers, Emanuel P.
Format: Online
Language:English
Published: BioMed Central 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929762/