Alzheimer’s disease AdvaxCpG- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological molecules

Alzheimer’s disease AdvaxCpG- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological molecules

Although β-amyloid (Aβ) may be the primary driver of Alzheimer’s disease (AD) pathology, accumulation of pathological tau correlates with dementia in AD patients. Thus, the prevention/inhibition of AD may require vaccine/s targeting Aβ and tau simultaneously or sequentially. Since high antibody tite...

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Bibliographic Details
Main Authors: Davtyan, Hayk, Zagorski, Karen, Rajapaksha, Harinda, Hovakimyan, Armine, Davtyan, Arpine, Petrushina, Irina, Kazarian, Konstantin, Cribbs, David H., Petrovsky, Nikolai, Agadjanyan, Michael G., Ghochikyan, Anahit
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929459/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929459/

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