A Platform for Rapid, Quantitative Assessment of Multiple Drug Combinations Simultaneously in Solid Tumors In Vivo

While advances in high-throughput screening have resulted in increased ability to identify synergistic anti-cancer drug combinations, validation of drug synergy in the in vivo setting and prioritization of combinations for clinical development remain low-throughput and resource intensive. Furthermor...

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Bibliographic Details
Main Authors: Dey, Joyoti, Kerwin, William S., Grenley, Marc O., Casalini, Joseph R., Tretyak, Ilona, Ditzler, Sally H., Thirstrup, Derek J., Frazier, Jason P., Pierce, Daniel W., Carleton, Michael, Klinghoffer, Richard A.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928803/