Diagnostic Impact of Cerebrospinal Fluid Biomarker (Pre-)Analytical Variability in Alzheimer’s Disease

Intra- and inter-laboratory variability of cerebrospinal fluid (CSF) biomarker analyses remains an important issue. We investigated the clinical-diagnostic impact of CSF biomarker concentration shifts in mild cognitive impairment (MCI) and autopsy-confirmed Alzheimer’s disease (AD) dementia patients...

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Bibliographic Details
Main Authors: Niemantsverdriet, Ellis, Goossens, Joery, Struyfs, Hanne, Martin, Jean-Jacques, Goeman, Johan, De Deyn, Peter Paul, Vanderstichele, Hugo, Engelborghs, Sebastiaan
Format: Online
Language:English
Published: IOS Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927863/