Osteopontin deficiency reduces kidney damage from hypercholesterolemia in Apolipoprotein E-deficient mice

Hypercholesterolemia is a well-established risk factor for kidney injury, which can lead to chronic kidney disease (CKD). Osteopontin (OPN) has been implicated in the pathology of several renal conditions. This study was to evaluate the effects of OPN on hypercholesterolemia induced renal dysfunctio...

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Bibliographic Details
Main Authors: Pei, Zouwei, Okura, Takafumi, Nagao, Tomoaki, Enomoto, Daijiro, Kukida, Masayoshi, Tanino, Akiko, Miyoshi, Ken-ichi, Kurata, Mie, Higaki, Jitsuo
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926090/