Synthesis of Phthalimide Derivatives as Potential PPAR-γ Ligands

Synthesis of Phthalimide Derivatives as Potential PPAR-γ Ligands

Paecilocin A, a phthalide derivative isolated from the jellyfish-derived fungus Paecilomyces variotii, activates PPAR-γ (Peroxisome proliferator-activated receptor gamma) in rat liver Ac2F cells. Based on a SAR (Structure-activity relationships) study and in silico analysis of paecilocin A-mimetic d...

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Bibliographic Details
Main Authors: Eom, So Hyeon, Liu, Sen, Su, Mingzhi, Noh, Tae Hwan, Hong, Jongki, Kim, Nam Deuk, Chung, Hae Young, Yang, Min Hye, Jung, Jee H.
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926071/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926071/

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