AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity

AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity

The receptor tyrosine kinase (RTK) AXL is induced in response to type I interferons (IFNs) and limits their production through a negative feedback loop. Enhanced production of type I IFNs in Axl-/-dendritic cells (DCs) in vitro have led to speculation that inhibition of AXL would promote antiviral r...

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Bibliographic Details
Main Authors: Schmid, Edward T, Pang, Iris K, Carrera Silva, Eugenio A, Bosurgi, Lidia, Miner, Jonathan J, Diamond, Michael S, Iwasaki, Akiko, Rothlin, Carla V
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924996/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924996/

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