Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome
Integrins αvβ3 and αvβ5 regulate angiogenesis and invasiveness in cancer, potentially by modulating activation of the transforming growth factor (TGF)-β pathway. The randomized phase III CENTRIC and phase II CORE trials explored the integrin inhibitor cilengitide in patients with newly diagnosed gli...
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Bibliographic Details
| Main Authors: |
Weller, Michael,
Nabors, Louis Burt,
Gorlia, Thierry,
Leske, Henning,
Rushing, Elisabeth,
Bady, Pierre,
Hicking, Christine,
Perry, James,
Hong, Yong-Kil,
Roth, Patrick,
Wick, Wolfgang,
Goodman, Simon L.,
Hegi, Monika E.,
Picard, Martin,
Moch, Holger,
Straub, Josef,
Stupp, Roger |
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| Format: | Online
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| Language: | English |
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| Published: |
Impact Journals LLC
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924768/
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