Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade

Meningiomas are frequent central nervous system tumors. Although most meningiomas are benign (WHO grade I) and curable by surgery, WHO grade II and III tumors remain therapeutically challenging due to frequent recurrence. Interestingly, relapse also occurs in some WHO grade I meningiomas. Hence, we...

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Bibliographic Details
Main Authors: Schmidt, Melissa, Mock, Andreas, Jungk, Christine, Sahm, Felix, Ull, Anna Theresa, Warta, Rolf, Lamszus, Katrin, Gousias, Konstantinos, Ketter, Ralf, Roesch, Saskia, Rapp, Carmen, Schefzyk, Sebastian, Urbschat, Steffi, Lahrmann, Bernd, Kessler, Almuth F., Löhr, Mario, Senft, Christian, Grabe, Niels, Reuss, David, Beckhove, Philipp, Westphal, Manfred, von Deimling, Andreas, Unterberg, Andreas, Simon, Matthias, Herold-Mende, Christel
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924735/