Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion

Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion

Endothelial connexin40 (Cx40) contributes to regulate the structure and function of vessels. We have examined whether the protein also modulates the altered growth of vessels in tumor models established in control mice (WT), mice lacking Cx40 (Cx40−/−), and mice expressing the protein solely in endo...

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Bibliographic Details
Main Authors: Alonso, Florian, Domingos-Pereira, Sonia, Le Gal, Loïc, Derré, Laurent, Meda, Paolo, Jichlinski, Patrice, Nardelli-Haefliger, Denise, Haefliger, Jacques-Antoine
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924695/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924695/

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