Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes

To shed light into the molecular bases of B-lineage acute lymphoblastic leukemia lacking known fusion transcripts, i.e. BCR-ABL1, ETV6-RUNX1, E2A-PBX1, and MLL rearrangements (B-NEG ALL) and the differences between children, adolescents/young adults (AYA) and adults, we analyzed 168 B-NEG ALLs by ge...

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Bibliographic Details
Main Authors: Messina, Monica, Chiaretti, Sabina, Wang, Jiguang, Fedullo, Anna Lucia, Peragine, Nadia, Gianfelici, Valentina, Piciocchi, Alfonso, Brugnoletti, Fulvia, Di Giacomo, Filomena, Pauselli, Simona, Holmes, Antony B., Puzzolo, Maria Cristina, Ceglie, Giulia, Apicella, Valerio, Mancini, Marco, te Kronnie, Geertruy, Testi, Anna Maria, Vitale, Antonella, Vignetti, Marco, Guarini, Anna, Rabadan, Raul, FoĆ , Robin
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924686/