Effects of Low Amyloid-β (Aβ) Concentration on Aβ1–42 Oligomers Binding and GluN2B Membrane Expression

Numerous studies have shown that amyloid-β (Aβ) modulate intracellular metabolic cascades and an intracellular Ca2+ homeostasis and a cell surface NMDA receptor expression alteration in Alzheimer’s disease (AD). However most of these findings have been obtained by using non-physiological Aβ concentr...

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Bibliographic Details
Main Authors: Gilson, Virginie, Mbebi-Liegeois, Corinne, Sellal, François, de Barry, Jean
Format: Online
Language:English
Published: IOS Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923730/