Indoleamine 2,3 Dioxygenase as a Potential Therapeutic Target in Huntington’s Disease

Within the past decade, there has been increasing interest in the role of tryptophan (Trp) metabolites and the kynurenine pathway (KP) in diseases of the brain such as Huntington’s disease (HD). Evidence is accumulating to suggest that this pathway is imbalanced in neurologic disease states. The KP...

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Bibliographic Details
Main Authors: Mazarei, Gelareh, Leavitt, Blair R.
Format: Online
Language:English
Published: IOS Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923717/