Recent Advances in Diagnostic Strategies for Diabetic Peripheral Neuropathy
Diabetes is an increasing epidemic in Korea, and associated diabetic peripheral neuropathy (DPN) is its most common and disabling complication. DPN has an insidious onset and heterogeneous clinical manifestations, making it difficult to detect high-risk patients of DPN. Early diagnosis is recommende...
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Korean Endocrine Society
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923406/ |
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pubmed-4923406 |
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pubmed-49234062016-07-07 Recent Advances in Diagnostic Strategies for Diabetic Peripheral Neuropathy Won, Jong Chul Park, Tae Sun Review Article Diabetes is an increasing epidemic in Korea, and associated diabetic peripheral neuropathy (DPN) is its most common and disabling complication. DPN has an insidious onset and heterogeneous clinical manifestations, making it difficult to detect high-risk patients of DPN. Early diagnosis is recommended and is the key factor for a better prognosis and preventing diabetic foot ulcers, amputation, or disability. However, diagnostic tests for DPN are not clearly established because of the various pathophysiology developing from the nerve injury to clinical manifestations, differences in mechanisms according to the type of diabetes, comorbidities, and the unclear natural history of DPN. Therefore, DPN remains a challenge for physicians to screen, diagnose, follow up, and evaluate for treatment response. In this review, diagnosing DPN using various methods to assess clinical symptoms and/or signs, sensorineural impairment, and nerve conduction studies will be discussed. Clinicians should rely on established modalities and utilize current available testing as complementary to specific clinical situations. Korean Endocrine Society 2016-06 2016-05-27 /pmc/articles/PMC4923406/ /pubmed/27246283 http://dx.doi.org/10.3803/EnM.2016.31.2.230 Text en Copyright © 2016 Korean Endocrine Society http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Won, Jong Chul Park, Tae Sun |
| spellingShingle |
Won, Jong Chul Park, Tae Sun Recent Advances in Diagnostic Strategies for Diabetic Peripheral Neuropathy |
| author_facet |
Won, Jong Chul Park, Tae Sun |
| author_sort |
Won, Jong Chul |
| title |
Recent Advances in Diagnostic Strategies for Diabetic Peripheral Neuropathy |
| title_short |
Recent Advances in Diagnostic Strategies for Diabetic Peripheral Neuropathy |
| title_full |
Recent Advances in Diagnostic Strategies for Diabetic Peripheral Neuropathy |
| title_fullStr |
Recent Advances in Diagnostic Strategies for Diabetic Peripheral Neuropathy |
| title_full_unstemmed |
Recent Advances in Diagnostic Strategies for Diabetic Peripheral Neuropathy |
| title_sort |
recent advances in diagnostic strategies for diabetic peripheral neuropathy |
| description |
Diabetes is an increasing epidemic in Korea, and associated diabetic peripheral neuropathy (DPN) is its most common and disabling complication. DPN has an insidious onset and heterogeneous clinical manifestations, making it difficult to detect high-risk patients of DPN. Early diagnosis is recommended and is the key factor for a better prognosis and preventing diabetic foot ulcers, amputation, or disability. However, diagnostic tests for DPN are not clearly established because of the various pathophysiology developing from the nerve injury to clinical manifestations, differences in mechanisms according to the type of diabetes, comorbidities, and the unclear natural history of DPN. Therefore, DPN remains a challenge for physicians to screen, diagnose, follow up, and evaluate for treatment response. In this review, diagnosing DPN using various methods to assess clinical symptoms and/or signs, sensorineural impairment, and nerve conduction studies will be discussed. Clinicians should rely on established modalities and utilize current available testing as complementary to specific clinical situations. |
| publisher |
Korean Endocrine Society |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923406/ |
| _version_ |
1613600372978352128 |