Generation of Pediatric Leukemia Xenograft Models in NSG-B2m Mice: Comparison with NOD/SCID Mice

Generation of orthotopic xenograft mouse models of leukemia is important to understand the mechanisms of leukemogenesis, cancer progression, its cross talk with the bone marrow microenvironment, and for preclinical evaluation of drugs. In these models, following intravenous injection, leukemic cells...

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Bibliographic Details
Main Authors: Gopalakrishnapillai, Anilkumar, Kolb, E. Anders, Dhanan, Priyanka, Bojja, Aruna Sri, Mason, Robert W., Corao, Diana, Barwe, Sonali P.
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921874/