An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection

An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection

Salmonella Typhimurium (S.Tm) is a common cause of self-limiting diarrhea. The mucosal inflammation is thought to arise from a standoff between the pathogen's virulence factors and the host's mucosal innate immune defenses, particularly the mucosal NAIP/NLRC4 inflammasome. However, it had...

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Bibliographic Details
Main Authors: Müller, Anna A., Dolowschiak, Tamas, Sellin, Mikael E., Felmy, Boas, Verbree, Carolin, Gadient, Sandra, Westermann, Alexander J., Vogel, Jörg, LeibundGut-Landmann, Salome, Hardt, Wolf-Dietrich
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920399/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920399/

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