LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV

LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV

Persistence of latent, replication-competent Human Immunodeficiency Virus type 1 (HIV-1) provirus is the main impediment towards a cure for HIV/AIDS (Acquired Immune Deficiency Syndrome). Therefore, different therapeutic strategies to eliminate the viral reservoirs are currently being explored. We h...

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Bibliographic Details
Main Authors: Vranckx, Lenard S., Demeulemeester, Jonas, Saleh, Suha, Boll, Annegret, Vansant, Gerlinde, Schrijvers, Rik, Weydert, Caroline, Battivelli, Emilie, Verdin, Eric, Cereseto, Anna, Christ, Frauke, Gijsbers, Rik, Debyser, Zeger
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919729/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919729/

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