PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase*

PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase*

PR domain-containing protein 7 (PRDM7) is a primate-specific histone methyltransferase that is the result of a recent gene duplication of PRDM9. The two proteins are highly homologous, especially in the catalytic PR/SET domain, where they differ by only three amino acid residues. Here we report that...

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Bibliographic Details
Main Authors: Blazer, Levi L., Lima-Fernandes, Evelyne, Gibson, Elisa, Eram, Mohammad S., Loppnau, Peter, Arrowsmith, Cheryl H., Schapira, Matthieu, Vedadi, Masoud
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919437/

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