Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon Cancer
Colorectal cancers (CRCs) form a disorganized hierarchy of heterogeneous cell populations on which current chemotherapy regimens fail to exert their distinctive cytotoxicity. A small sub-population of poorly differentiated cancer stem-like cells (CSCs), also known as cancer initiating cells, may exh...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Springer US
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919387/ |