Role of the Long Non-Coding RNA MAPT-AS1 in Regulation of Microtubule Associated Protein Tau (MAPT) Expression in Parkinson's Disease

Role of the Long Non-Coding RNA MAPT-AS1 in Regulation of Microtubule Associated Protein Tau (MAPT) Expression in Parkinson's Disease

Studies investigating the pathogenic role of the microtubule associated protein tau (MAPT) gene in Parkinson’s disease (PD) have indicated that DNA methylation of the promoter region is aberrant in disease, leading to dysregulated MAPT expression. We examined two potential regulators of MAPT gene ex...

Full description

Bibliographic Details
Main Authors: Coupland, Kirsten G., Kim, Woojin S., Halliday, Glenda M., Hallupp, Marianne, Dobson-Stone, Carol, Kwok, John B. J.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919105/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919105/

Similar Items