Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease

Common neurodegenerative proteinopathies, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), are characterized by the misfolding and aggregation of toxic protein species, including the amyloid beta (Aß) peptide, microtubule-associated protein Tau (Tau), and alpha-synuclein (αSyn) protein...

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Bibliographic Details
Main Authors: Chouhan, Amit K., Guo, Caiwei, Hsieh, Yi-Chen, Ye, Hui, Senturk, Mumine, Zuo, Zhongyuan, Li, Yarong, Chatterjee, Shreyasi, Botas, Juan, Jackson, George R., Bellen, Hugo J., Shulman, Joshua M.
Format: Online
Language:English
Published: BioMed Central 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918017/