Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses

Clusterin (Clu), an extracellular chaperone, exhibits characteristics of soluble innate immunity receptors, as assessed by its ability to bind some bacteria strains. In this study, we report that Clu also binds specifically to late apoptotic cells but not to live, early apoptotic, or necrotic cells....

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Bibliographic Details
Main Authors: Cunin, P, Beauvillain, C, Miot, C, Augusto, J-F, Preisser, L, Blanchard, S, Pignon, P, Scotet, M, Garo, E, Fremaux, I, Chevailler, A, Subra, J-F, Blanco, P, Wilson, M R, Jeannin, P, Delneste, Y
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917652/