Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval

There has been a growing interest in the study of epigenetic mechanisms to elucidate the molecular bases of human brain-related diseases and disorders. Frequently, researchers utilize post-mortem tissue with the assumption that post-mortem tissue decay has little or no effect on epigenetic marks. Al...

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Bibliographic Details
Main Authors: Gross, Jeffrey A., Nagy, Corina, Lin, Li, Bonneil, Éric, Maheu, Marissa, Thibault, Pierre, Mechawar, Naguib, Jin, Peng, Turecki, Gustavo
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917525/